DOSE8: AN APPLICATION ENABLING THE TIME EFFICIENT DOSIMETRY CALCULATION ACCORDING TO THE MIRD-SCHEME Elbischger
نویسنده
چکیده
Dosimetry is the process of calculating the effective radioactive dose that is applied to tumors and organs respectively as a patient undergoes a peptide receptor radionuclide therapy. This work presents the novel application software ‘DoSE8’ that was developed from our group and that incorporates all necessary image processing steps (registration and segmentation) and data handling for (partly) automating and calculating complete dosimetries. ‘DoSE8’ significantly accelerates dosimetry calculation from six hours to only fifteen minutes per patient and, therefore, makes it possible to perform dosimetry in clinical routine at all. Furthermore, it enables the calculation of a sufficient amount of dosimetries to develop reliable prediction models that allow predicting the proper amount of radioactive substances to be injected directly from body indices and before the actual medical treatment takes place.
منابع مشابه
Dosimetry of Nano-Radio-Ytterbium Therapy by MIRD and MCNP methods for humans’ organs
Introduction: Nano radio-pharmaceutical therapy (NRPT) is a new method for solid tumor therapy. The treatment uses a radioactive form of radionuclide encapsulated in the poly amido amine dendrimers. The poly (amidoamine) (PAMAM) dendrimers have attracted attentions for cancer treatment by their characteristics of targeted drug carriers, delivery agents, and imaging agents in hu...
متن کاملDevelopment of Prototype Iranian male pelvic phantom for internal dosimetry
Introduction: Existing phantoms have been constructed based on Caucasian, non-Caucasian and race-specific datasets. According to previous studies made efforts to present Korean- specific phantoms and Chinese female phantom based on CVH dataset due to compare the resulting internal dosimetry with the Caucasian based data showed possible racial difference in human anatomy between ...
متن کاملPatient dose calculation software in nuclear medicine [Persian]
Introduction: Radioactive materials deliver internal radiation dose to patients in nuclear medicine. Manual internal radiation dose assessment is a complicated method. Introduction of a simple dose calculation software is the main goal of the present study. Methods: Using the best current data in internal dose calculation (S-Factors) recommended by ICRP and by cons...
متن کاملDetermination of organ doses in radioiodine therapy using medical internal radiation dosimetry (MIRD) method
Background: Radioiodine therapy has proven to be an effective method in the treatment of patients with differentiated thyroid carcinoma after thyroidectomy. The scope of this study is to describe a method to obtain the dose of organs using medical internal radiation dosimetry (MIRD) method. At the end, the results of MIRD calculations were compared with thermoluminescent dosimeter (TLD...
متن کاملInRaDoS: An internal radiation dosimetry computer program
Introduction: Internal radiation dosimetry is important from a radiation protection point of view and can help to optimize the radiation dose delivered to the workers, public, and patients. It has a rather simple protocol but needs a large amount of data. Therefore, it is difficult to do on a routine basis. The use of computer programs makes internal radiation dosimetry simpler...
متن کامل